SUMMER SCHOOL – Understanding the many shapes of inflammation: from bench to bedside

Inflammation is a multifaceted biological process that plays a critical role in the body defense against infection and injury.

However, when dysregulated, inflammation can drive the development of numerous chronic diseases, such as autoimmune disorders, cardiovascular diseases, cancer, and neurodegenerative conditions. The summer school focuses on exploring the many “shapes” or forms that inflammation can take, from acute, beneficial responses to chronic, pathogenic processes. The program covers a wide array of topics, beginning with the fundamental biological mechanisms of inflammation. Participants will explore the cellular and molecular pathways involved, the interplay between innate and adaptive immunity, with a focus on how these systems collaborate to mediate inflammation. A distinguishing feature of this program is its “bench to bedside” approach, which underscores the importance of translating basic research into clinical practice. Participants will gain insights

into how cutting-edge research informs the development of new therapies and how clinicians apply these findings in the treatment of inflammatory diseases. Topics such as immunotherapies, biologic drugs targeting specific inflammatory pathways, and the use of biomarkers for diagnosing and monitoring inflammatory conditions will be highlighted. In addition to theoretical learning, the program incorporates hands-on workshops designed to give participants practical experience in investigating inflammation. Workshops may include laboratory techniques such as flow cytometry, RNA sequencing, CRISPR-based

gene editing, and proteomics, all of which are essential tools in modern inflammation research. These sessions allow participants to directly apply what they’ve learned in lectures, gaining technical skills that are valuable for their research careers. This

aspect of the program is particularly beneficial for participants interested in translational medicine, as it demonstrates how laboratory discoveries can impact patient care.